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Though their function is unclear, GIP receptors are also present in other organs such as the heart, kidneys, and skin [6]

Once the drugs are approved for use, they must be monitored carefully for any new adverse events and to ensure they continue to be effective at controlling diabetes over time [42]

Altogether, about 1 in 8 US adults say they're currently taking one of the medicines, according to data from health policy research group KFF

The only GIP receptor antagonist administered in humans for a longer period, is the aforementioned AMG133, which is an antagonistic GIP receptor antibody conjugated to two agonistic GLP-1 receptor peptide analogues (84)
