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Our prior blog GLP-1 Drugs: FDA Sued Over Removing Tirzepatide from the Drug Shortage List discusses the litigation

Knudsens work found that liraglutide was internalized by proopiomelanocortin (POMC)/cocaine- and amphetamine-regulated transcript (CART) neurons and indirectly inhibits neuropeptide Y (NPY) and agouti-related peptide (AgRP) neurons through Gamma Amino Butyric Acid (GABA) dependent signaling

Below, we compare a few of the main deciding factors between the two for you

By application, type 2 diabetes dominates with over 52% share, followed by obesity with approximately 28%, while cardiovascular and cerebrovascular diseases contribute around 9%, NASH holds nearly 6%, and Alzheimers disease accounts for about 5% share