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Recent reports suggest that as of 2022, 12% of adults in the United States have taken a GLP-1 agonist for weight loss at some point

The breast cancer-related lymphedema multidisciplinary approach: Algorithm for conservative and multimodal surgical treatment

Furthermore, hormonal adaptations contribute significantly to plateaus

Also, read the accompanying editorial by David Felson: Source Reference: Felson DT "Glucagon-like peptide-1 receptor agonists and osteoarthritis" N Engl J Med 2024

Understanding these dynamics is critical for optimizing the use of GLP-1based agents in disorders with central components, including neurodegeneration, psychiatric illness, and addiction