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Consult Your Healthcare Provider: If constipation persists or becomes bothersome, don't hesitate to discuss it with your healthcare provider

In the GLP-1 vs DPP-4 inhibitor cohort (2009-2022), we identified 108,322 new users of GLP-1 RAs and 55,411 new users of DPP-4 inhibitors using the National Prescription Registry

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Similar evidence from another study in 2018 showed that GLP-1 RAs modulate metabolism similar to statins by suppressing HMG-CoA reductase and SREBP-1C (sterol regulatory element-binding protein 1C) [64]

In fact, in a search carried out on the ClinicalTrials.gov website (20 November 2024), a total of 458 registered studies for the use of SMG were found, many of them still active, either recruiting participants or that had not yet started the recruitment phase