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Does Wegovy increase resting heart rate? Yes, Wegovy increases mean resting heart rate by approximately 1.64.0 beats per minute compared to placebo, according to STEP trial data

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Its endogenous form has a plasma half-life of only 2-3 minutes due to rapid degradation by dipeptidyl peptidase-4 (DPP-4) and renal clearance

In PIONEER clinical trial programme, 9543 subjects were enrolled and 5707 subjects have been randomized to oral semaglutide
