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claims data (January 2019 to June 2025) in a retrospective cohort study
doi: 10.1016/j.pediatrneurol.2014.05.013

Tirzepatide is the active ingredient in the brand-name medications Zepbound and Mounjaro , and its a combination of a GLP-1 and a GIP (glucose-dependent insulinotropic polypeptide)

A pro-diabetogenic mtDNA polymorphism in the mitochondrial-derived peptide, MOTS-c