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Their primary mechanisms of action include: Enhancing glucose-dependent insulin secretion from pancreatic beta cells Suppressing glucagon release , which reduces hepatic glucose production Slowing gastric emptying , leading to prolonged satiety Acting on appetite centres in the brain to reduce food intake These combined effects result in improved glycaemic control, reduced HbA1c levels, and significant weight loss in many patients

If a prescription is written, medication is fulfilled through partner pharmacies and shipped to the patient's address

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Patnoe said diabetes care and education specialists should screen patients with diabetes for eating disorder thoughts and behaviors before and after starting GLP-1 therapy, and therapy should start at the lowest dose possible where hunger signals are maintained, and titration should be slow