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(2021) demonstrated that GLP1 receptor activation with systemically administered Ex4 dilated cortical arterioles, increased cerebral blood flow and increased cortical oxygen partial pressure in rat

A 2024 trial showed significant improvements in fibromyalgia symptoms with this approach

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For differential expression testing, the R package DESeq2 (v.1.30.1) was used to identify differentially expressed genes

In addition, post-hoc sensitivity analyses were performed by excluding the prediabetic population (SELECT trial [8]) in Fig
