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Nausea and vomiting, common side effects of GLP-1 therapy, can lead to volume depletion, further straining kidney function when paired with medications that inhibit the renin-angiotensin system (RAAS)

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60 However, in humans, early studies demonstrated that GLP-2 administration for five weeks increased spinal BMD in people with short bowel syndrome, 62 but had limited overall bone benefits

Table 1 integrates the mechanisms described in Chapter 5 with the relapse trajectories summarized here, highlighting how behavioral and psychosocial processes intersect with biological rebound

If not, maybe staying on a low dose would be an okay trade-off for getting to enjoy this life phase at a weight Im more comfortable with