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Those with reduced appetite due to tirzepatide's effects must make conscious efforts to maintain fluid intake despite decreased thirst signals

Most experience relief of symptoms within two to four weeks as the body adjusts, and the mind typically follows suit

[DOI] [PMC free article] [PubMed] [Google Scholar] 36.Kim M, Platt MJ, Shibasaki T, Quaggin SE, Backx PH, Seino S, Simpson JA, Drucker DJ

Conversely, stress and dysbiosis reduce this metabolic loop
doi: 10.1345/aph.1R501