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This neurobiological shift would represent a functional change in food reward rather than a peripheral taste bud alteration, though human evidence remains limited

Contraindications Tolcapone is contraindicated in: Active liver disease Elevated baseline liver enzymes History of tolcapone-induced hepatotoxicity Severe hepatic impairment Hypersensitivity To view or add a comment, sign in Excellent graphic overview on pharmacological and clinical aspects of oral semaglutide in T2DM by Ney Carter Borges MD M.Sc

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[DOI] [PubMed] [Google Scholar] 667.Donahey J.C., van Dijk G., Woods S.C., Seeley R.J
