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Among adults who have had a documented substance overdose, those who started on a GLP-1 had a 39% lower risk of a repeat overdose within three years of their overdose compared to patients who were never prescribed a GLP-1

Alcohol consumption while taking GLP-1 medications requires careful consideration

Can be used with GLP-1 medications

GLP-1 receptors located in hypothalamic and brainstem centers are known to influence hunger signaling and satiety pathways, while GIP and glucagon receptor signaling contribute to nutrient sensing and metabolic feedback mechanisms

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