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Our studies revealed key signaling mechanisms underlying the role of GPR17 in regulating GLP-1 secretion and suggest future opportunities for pharmacologically targeting GPR17 with inverse agonists to maximize GLP-1 secretion ![Graphical Abstract][1] Graphical Abstract ### Competing Interest Statement The authors have declared no competing interest

Pharma giant Novo Nordisk has officially announced the launch of an oral version of its blockbuster drug

While the FDA says compounded drugs can serve an important medical need for patients, the agency does not approve these new formulations, increasing the risk of complications.

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