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Between-study heterogeneity was very high (I = 99.21%) although sensitivity analysis revealed that the findings were robust

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In line with evidence accrued in patients with T2D, incretin-based therapies produced a favorable effect on traditional cardiovascular risk factors, such as lipids and blood pressure, and even reduced the risk of major cardiovascular events and heart failure-related events in individuals with obesity, as recently demonstrated for the first time in the SELECT trial with semaglutide 2.4mg once-weekly

elegans germline, distal niche cells provide a Notch signal to promote stem cell proliferation