what is a glp-1 agonist Holding Agonists Prior to Elective Procedures Glucagon-like peptide-1 - Wikipedia
Description
Truncated glucagon-like peptide I, an insulin-releasing hormone from the distal gut
In the largest clinical trial that tested Wegovy before its FDA approval, people taking the highest dose (2.4 milligrams) lost, on average, more than 12% of their body weight over 17 months

Its efficacy and safety were evaluated in a 56-week, randomized, placebo-controlled trial involving adolescents aged 12 to 18 years with obesity

These effects contribute to weight loss that varies by agent and dosetypically ranging from 5-8% with liraglutide 3 mg (Saxenda), up to 15% with semaglutide 2.4 mg (Wegovy), and potentially up to 20% with higher doses of tirzepatide (Zepbound)

Prescription drugs are standardized to a potent effect, Undeberg says
