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QUESTIONING THE ROLE OF FAT DISTRIBUTION There is a strong association between abdominal fat deposition and health outcomes, including an increased risk of type 2 diabetes, adverse cardiovascular effects, insulin resistance, and dyslipidemia (1012)

And while they can positively affect general digestive issues, we know now that bitter substances do so much more

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However, given that orforglipron will be a prescription medication, physicians could potentially prescribe it off-label for diabetes prior to formal diabetes approval, a common practice in the GLP-1 space