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"These are very impactful outcomes that support the widespread benefits of this class of medications in this high-risk population. Zhang agreed, saying it's possible that the data could help change practice

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In other cases, the drugs help the body handle blood sugar and fat, making people more metabolically flexible and biochemically more youthful, said Dr

GLP-1's influence extends beyond just hunger signals

Marsha Novick: Mild nausea, constipation, diarrhea, fatigue, and low appetite are fairly common with GLP-1 medications like semaglutide (Wegovy) and tirzepatide (Zepbound), especially in the first few days after an injection or after a dose increase