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Part 1 of a phase III trial investigating semaglutide for the treatment of MASH demonstrated resolution of steatohepatitis with no worsening of fibrosis in 63% of the semaglutide group, compared with 34% in the placebo group (68)
The high monthly cost of these medications poses a significant barrier, particularly in resource-limited settings
doi: 10.2337/db12-1116 58 KleinertMSachsSHabeggerKMHofmannSMMullerTD
Each has advantages and trade-offs
18 Connectivity Map (CMap) is a crucial tool for drug repurposing by screening compounds that can generate gene expression profiles similar to that of the target drug
