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The British Heart Foundation funded the trial, which also involved experts from University College London
doi: 10.1371/journal.pone.0047936
In SURMOUNT-1 the 15 mg arm averaged 22.5% body weight loss at 72 weeks, only modestly higher than the 10 mg arm at 21.4%
Tirzepatide appears to have an edge in total efficacy, but individual response varies considerably
Individual genetic variations in GLP1R sensitivity, which PlexusDx can identify through the Precision Peptide Genetic Test, may influence both the onset timing and duration of symptoms
