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Diabetes Obes Metab (2016) 18:22435
However, this might explain why, despite having fasted for a median duration of 15.8 hours (intequartile range 12.6-18.5) from solid food and 11.0 hours (interquartile range 5.6-14
)
The most common study treatment-related adverse effects were GI disorders such as vomiting, abdominal distention, and nausea, however, mostly of mild intensity
Fatigue on tirzepatide and semaglutide-related fatigue can create a cycle where poor sleep worsens digestive symptoms, digestive discomfort disrupts sleep further, and the combined effect makes side effects harder to tolerate
