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GLP-1 has a very short half-life of approximately 1-2 minutes in circulation, as it is rapidly degraded by the enzyme dipeptidyl peptidase-4 (DPP-4)

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It's a short chain of amino acids, and its only job is to deliver a brief, specific instruction: tell this cell to release a hormone, tell that one to start repairing tissue, tell the brain the stomach is full

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