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Description
Large-scale pharmacoepidemiological data has not demonstrated a statistically significant increase in suicidal behaviour but there are important signals in specific subgroups, particularly those already on antidepressants or benzodiazepines

Currently, there are ten classes of orally available pharmacological agents to treat T2DM: 1) sulfonylureas, 2) meglitinides, 3) metformin (a biguanide), 4) thiazolidinediones (TZDs), 5) alpha glucosidase inhibitors, 6) dipeptidyl peptidase IV (DPP-4) inhibitors, 7) bile acid sequestrants, 8) dopamine agonists, 9) sodium-glucose transport protein 2 (SGLT2) inhibitors and 10) oral glucagon like peptide 1 (GLP-1) receptor agonists

It targets two hormone receptors GLP-1 and GIP helping reduce appetite, stabilise blood sugar, and promote sustained fat loss

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