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Research to better understand and ultimately mitigate this heightened susceptibility is an important priority for new drug development in this area, and novel approaches to model the impact of endogenous hormone signaling will be critical to developing better treatments for more people
GLP-1RAs show modest SBP reductions (1.85.1 mmHg) and minimal DBP effects (~0.5 mmHg), though tirzepatide shows greater efficacy (~10.6 mmHg) in select populations
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