glp-1 receptor agonist use and risk of suicide death GLP-1s Like Ozempic May Be a New Treatment for Addiction Frontiers | Suicidality as a

If you do have type 2 diabetes, your clinician will decide which brand and indication fits your situation better

Aung MM, et al

The approved form of the once weekly exenatide [Bydureon] has a black box warning discussing the thyroid issue

Effect of once-weekly semaglutide on the counterregulatory response to hypoglycaemia in people with type 2 diabetes: a randomized, placebo-controlled, double-blind, crossover trial

Allosteric (off active site) activators were reported in the literature as early as the mid-2000s, but they had poor potency, poor pharmacokinetics, species-selective activity (human but not rodent), and none made it close to the clinic