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54.FDA Guidance for Industry Diabetes Mellitus Evaluating Cardiovascular Risk in New Antidiabetic Therapies to Treat Type 2 Diabetes

Some practitioners implement cycling to theoretically prevent receptor desensitization, provide physiological breaks, or manage costs, though evidence supporting these approaches is limited

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Some state or regional plans may have more lenient or more strict policies regarding the off-label use of high-cost drugs

Health Canada understands that there is considerable interest in lowering costs associated with this highly prescribed drug by introducing generic versions, spokesperson Mark Johnson said in an email to The Canadian Press