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After discontinuing its internal GLP-1 in May of 2025 for causing liver issues, Pfizer won a bidding war against seven other companies for Metsera, which is developing a variety of incretin assets, paying $10 billion in one of 2025s largest M&A deals

Patience helps

However, as aforementioned, due to the lack of a placebo group, high baseline C-peptide levels, and concomitant use of a restricted carbohydrate diet, these results are difficult to interpret or extrapolate to other populations

Looking Ahead The future of GLP-1 receptor agonists is incredibly promising

Marc Jean-Gilles, DO, FACOG , at Abundant Life Healthcare for proper guidance and treatment