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The finding challenges long-held assumptions about how GLP-1 medicines such as Ozempic and Wegovy work in the liver, and could reshape how physicians treat metabolic liver disease, a condition projected to affect nearly two billion people worldwide by 2050.
Background GLP-1 receptor agonists (GLP-1RA) are effective for glycemic control and cardiometabolic outcomes, but their infectious safety, particularly regarding herpes simplex virus (HSV) and herpes zoster (HZ), is underexplored
