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Medication is only the tip of the iceberg
Glucagon-Like Peptide-1 Receptor Agonist Inhibits Asymmetric Dimethylarginine Generation in the Kidney of Streptozotocin-Induced Diabetic Rats by Blocking Advanced Glycation End ProductInduced Protein Arginine Methyltranferase-1 Expression
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Its major functions include: 1
Dehydration, a common side effect due to increased activity and reduced thirst signals, may also cause the body to retain water, mimicking weight gain
The alternating hypothesis suggests that cycling between a pure GLP-1 agonist and a dual GIP/GLP-1 agonist could prevent or delay this tolerance
