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Meanwhile, in the latest animal studies, some researchers found that exendin-4 can reduce levels of serum VLDL cholesterol and low-density lipoprotein cholesterol (LDL-C) by reducing liver sterol regulatory element binding protein 2 (SREBP2) level and cholesterol absorption [75]

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Contact your prescriber promptly if you experience severe vomiting or signs of dehydration

Current clinical trials and future research directions As of early 2026, no active clinical trials are specifically investigating tirzepatide for autoimmune disease treatment

(2016) 5:e002804
