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Heat accelerates molecular breakdown, reducing bioavailability and clinical efficacy

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It is important to note that headaches are common in the general population, and establishing a definitive causal link to any medication requires careful consideration of timing, pattern, and alternative explanations

Rybelsus works by mimicking the action of the naturally occurring hormone GLP-1, which stimulates insulin secretion in response to food intake, suppresses glucagon release (a hormone that raises blood sugar), and slows gastric emptying