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Tirzepatide (Mounjaro), a dual GIP/GLP-1 receptor agonist for the management of type 2 diabetes

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After 56 weeks: Placebo group lost 1.6% of body weight Starting dose (3.75/23 mg) group lost 5.1% of body weight Top dose (15/92 mg) group lost 10.9% of body weight Beyond weight loss, the CONQUER trial showed significant improvements in blood pressure, waist circumference, lipid profiles, glycemic parameters, and inflammatory biomarkers compared to placebo

These physical changes can have a significant emotional impact

GLP-1 RAs, originally developed to strengthen insulin secretion and manage blood glucose levels, have shown impressive benefits on the far side of glycemic control