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As a result, short-acting compared to long-acting GLP-1RAs are less effective in reducing fasting glucose and improving overall glucose control but are more effective in delaying gastric emptying and reducing glycemic excursion after meal ingestion (67)

About half think the medication should be affordable and covered by insurance

doi: 10.1038/304368a0 7 HolstJJOrskovCNielsenOVSchwartzTW

This mouse line was originally developed by crossing humanized Glp-1r knockin mice (105) with MIP-Cre/ERT mice (106), both of which are on a C57BL/6 background

The renal pelvis was cannulated with a 32 G triple-lumen catheter (ReCathCo, Allison Park, PA) via the ureter for intrapelvic perfusion and withdrawal of infusate and monitoring of pelvic pressure