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Description
Combining GLP-1 receptor agonists is generally contraindicated

Data extraction The data extracted from each study included information on the first author, publication year, country, criteria for inclusion and exclusion, follow-up duration, baseline characteristics of participants, drug history, lab data, treatment characteristics, and outcomes

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Everyone who takes a GLP-1 has their own issues that affect whether they stick with their regimen

In the CNS, endogenous GLP-1 acts primarily through vagal afferent signaling, transmitting information from the gastrointestinal tract to the brainstem [123, 124]
