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Emerging research suggests GLP-1s may directly affect the skin by reducing collagen production, accelerating glycation (which stiffens and weakens collagen fibers), and diminishing hydration levels

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A Meta-Analysis of Serious Adverse Events Reported With Exenatide and Liraglutide: Acute Pancreatitis and Cancer

Although direct evidence for GLP-1RA use in PsA remains limited, the inclusion of PsA populations in these tirzepatide trials represents a conceptual shift toward testing immunometabolic interventions in inflammatory arthritis rather than restricting their evaluation to skin disease alone

Whether youve been taking it for diabetes or weight management, if youve noticed some unwelcome changes to your bowel movements, know that youre not alone