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In mice and non-human primates, dual GLP-1R/GCGR (glucagon receptor) agonists have been shown to induce excellent glycemic control and significantly greater weight loss than liraglutide monotherapy, increasing energy expenditure and reducing total energy intake by 6070% [158]

In a study looking at the drug tirzepatide, people lost an average of 15%-20% of their body weight

Siebold and the other anonymous reviewer(s) for their contribution to the peer review of this work

Patients message their Care Team for dose adjustments, side effect guidance, and nutrition support
