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Glycemic control, pre-existing cardiovascular disease and risk of major cardiovascular events in patients with type 2 diabetes mellitus: a systematic review with meta-analysis of cardiovascular outcome trials vs intensive glucose control trials

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PMID: 56 Hernandez-AlvarezM

Overall, in adults with type 1 diabetes and CKD, RAS inhibition reduces the risks of progression of microalbuminuria to macroalbuminuria by approximately 50% and of serum creatinine doubling by 2030% [21]