retatrutide mechanism triple agonist glp-1 gip glucagon ly3437943 Agonism Based Therapies for Obesity | Current Cardiovascular Risk Reports retatrutide triple agonist glp-1 gip
Description
Association between bariatric surgery and macrovascular disease outcomes in patients with type 2 diabetes and severe obesity
The new findings add to a growing body of research suggesting that GLP-1 receptor agonists may influence mental health as well as metabolic health
Evidence synthesis: We integrate RCT evidence on weight and metabolic outcomes with exploratory findings on reproductive outcomes, highlighting key effect modifiers (baseline obesity/IR phenotype, concomitant metformin, and follow-up window)
10.1530/REP-15-0044 [DOI] [PubMed] [Google Scholar] 149.Ma X, Hayes E, Prizant H, Srivastava RK, Hammes SR, Sen A, et al
Under high glucose conditions, endothelial cells acquire the characteristics of fibroblasts, via endothelial-mesenchymal transition (EndMT)
