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The FDA has approved a label expansion for Wegovy based on a supplemental New Drug Application (sNDA) for the indication of reducing risks of major adverse cardiovascular events (MACE) including cardiovascular death, non-fatal heart attack (myocardial infarction) or non-fatal stroke in adults with either overweight or obesity and established cardiovascular disease (CVD).The approval is based on the SELECT cardiovascular outcomes trial, which demonstrated that Wegovy statistically significantly r

They are not always negative adverse reactions
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