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Taken together, the data support a cautious yet balanced interpretation

There is no established causal link between Mounjaro (tirzepatide) and increased yeast infection risk

The researchers suggested the benefits of GLP-1s before pregnancy could be negated or attenuated by the adverse effects of GLP-1 discontinuation. They added the higher risk for gestational weight gain may contribute to the increased risk for hypertensive disorders of pregnancy and gestational diabetes given the established relationship between gestational weight gain and adverse pregnancy outcomes. Maya told Healio that many individuals are on GLP-1s before pregnancy and are benefiting tremendously. Clinicians following these patients need to know that when their patients stop these medications for pregnancy, they are at risk for greater gestational weight gain and greater risk for gestational diabetes, hypertensive disorders of pregnancy and preterm delivery, she said

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Beyond weight and pain outcomes, the investigational agent also reduced several cardiovascular risk markers, including non-HDL cholesterol, triglycerides, hsCRP, and systolic blood pressure at the highest dose