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Staying at a lower effective dose that you tolerate well often produces better long-term outcomes than struggling with side effects at higher doses

Exercise also reduced systolic and diastolic blood pressure and led to decreased BMI in those who undertook more than six months of exercise

The SELECT trial is one of the largest cardiovascular outcome trials of its kind, involving over 17,600 participants with established cardiovascular disease who were overweight or obese but did not have diabetes (2 Trusted Source Semaglutide and cardiovascular outcomes by baseline and changes in adiposity measurements: a prespecified analysis of the SELECT trial Go to source)

In contrast, case 3 presented with multiple systemic risk factors commonly associated with NAION while having the largest BMO among the four cases

Monitor for symptoms of adverse effects or changes in disease symptoms that might suggest an interaction