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The report represented, to the researchers knowledge, the first documented case of complete erythromelalgia remission following GLP-1 receptor agonist therapy and may help generate hypotheses for future controlled studies in neurovascular pain syndromes

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Interestingly, these beneficial effects on inflammation and fibrosis, initially identified in models of diabetes, have now been extended to non-diabetic models of renal injury including the classical subtotal nephrectomy model (63), which had been used originally to define the renoprotective role of drugs that block the RAAS (69, 70)

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