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Without sufficient saliva, these particles linger, providing fuel for bacteria

In a Phase II study reported in 2024 involving 168 patients with NASH, moderate to advanced fibrosis (F2F3), and NAS 4, a significantly greater proportion of patients in the denifanstat group achieved the primary endpoint compared with placebo, with statistically meaningful improvements in fibrosis as well

Offered via a U.S.-based telehealth model, this program allows eligible adults to access prescription-grade GLP-1 medication without requiring insurance, while maintaining ongoing physician oversight

All had type 2 diabetes with an A1C level between 6.5% and 10%, meaning elevated blood glucose, and had either known atherosclerotic cardiovascular disease, chronic kidney disease, or both

This combined effect not only stabilizes blood sugar but also prolongs feelings of fullness