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tirzepatide effects of tirzepatide, a dual GIP and GLP-1 receptor agonist, on blood pressure, cardiac function, and sympathetic nervous system in stroke-prone spontaneously hypertensive rats Achieve Weight Loss with Tirzepatide
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Insufficient hydration can paradoxically worsen constipation and increase risk of intestinal obstruction, though this complication is rare

Delayed, fatal cardiotoxicity associated with bupropion and citalopram overdose

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She added the drugs have demonstrated long-term safety in clinical trials, with common side effects including nausea, diarrhea, vomiting, constipation, stomach pain, headache, tiredness, upset stomach, dizziness, feeling bloated, belching, gas, stomach flu and heartburn
