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Hathaway et al

De-escalation of anti-hypertensive drugs was more frequently observed in patients treated with semaglutide and likely masks a larger treatment effect

Zhao T, Parikh P, Bhashyam S, Bolukoglu H, Poornima I, Shen YT, Shannon RP: Direct effects of glucagon-like peptide-1 on myocardial contractility and glucose uptake in normal and postischemic isolated rat hearts

When your cells become resistant, your body compensates by producing more insulin

Historically, obesity was not such a huge problem
