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Coopman et al., 2010)

Diz-Chaves, Y., Herrera-Perez, S., Gonzalez-Matias, L

They can be an alternative for people not interested in these drugs, or can be combined with therapy to address side effects, improve adherence, and create a better overall quality of life, Rathi said.

This enhanced coupling facilitates a more efficient transfer of Ca 2+ from ER release sites (IP3Rs) to the mitochondrial matrix, activating Krebs cycle dehydrogenases and elevating cellular ATP levels

Screening for and treating nutritional deficiencies (vitamin B12, folate, iron, and where clinically indicated, vitamin D) and thyroid dysfunction is also important, as these can independently cause cognitive symptoms