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50 Gastrointestinal Motility Disorders: Gastric and Intestinal Manifestations GLP-1 RAs reduce GI motility and prolong intestinal transit time, effects that have raised concerns regarding an increased risk of gastroparesis, intestinal obstruction, or ileus
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Pretreatment with all agonists resulted in a blunted cAMP response to GLP-1 in INS-1 832/3 cells, this being least marked with exendin-phe1 (Fig
