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The FDA maintains the boxed warning because proving a negative, proving that something definitively does NOT cause cancer, requires decades of surveillance data

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The semaglutide dosage for weight loss does not have to mean 2.4 mg for everyone

Metabolic Adaptation and Hormonal Factors The issue: Certain metabolic and hormonal conditions, such as hypothyroidism, polycystic ovary syndrome (PCOS), or insulin resistance, can slow weight loss
