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Do not put the cap back on
Your GLP-1 and GIP receptors work together over seven days to suppress hunger hormones and slow gastric emptying

Split dosing is my recommendation when appetite suppression is not the number one priority, or to mitigate side effects

The SURMOUNT-4 follow-up analysis, published in JAMA Internal Medicine in 2025, found that weight regain after stopping tirzepatide was associated with reversal of improvements in blood pressure, blood glucose, cholesterol, and insulin sensitivity

It only takes one pint of water to make a pound on the scale
