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Gradual dose titration is the cornerstone of minimising gastrointestinal symptoms

Sacai H, Sasaki-Hamada S, Sugiyama A, et al

Long-term sustainability depends on continuing treatment, as weight typically returns when GLP-1 medications are discontinued

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For medications with flexible timing (liraglutide, weekly formulations), providers often suggest patients begin with the timing that best fits their schedule and monitor for side effects
