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Efficacy and safety of lixisenatide once-daily versus exenatide twice-daily in patients with type 2 diabetes insufficiently controlled on metformin: a 24-week, randomized, open-label, active-controlled study (GetGoal-X) // Diabetes Care

These cells are present all the way from the duodenum to the recturm

It is a fixed-dose combination product that contains naltrexone, an opioid antagonist, and bupropion, an aminoketone antidepressant

BMC Health Serv Res 25 , 1276 (2025)

However, studies have reported that GLP-1 exerts its effects on certain extrapancreatic tissues despite the absence of GLP-1R, which implies that this hormone may also act via currently unidentified receptors or mechanisms 2,7